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Sinemet (carbidopa-levodopa) is used to treat some symptoms of Parkinson's disease. It is most helpful in improving slow movement and muscle stiffness. 14 Jul 2017 Motor fluctuations in Parkinson's disease (PD) can be minimized by reducing oscillations in plasma levodopa levels [1]. One strategy proposed 25 Mar 2008Although Parkinson's disease is characterized by a loss of brain cells that contain and release the brain chemical (or neurotransmitter) dopamine, simple SINEMET® (carbidopa levodopa) is a combination of carbidopa and levodopa for SINEMET 25-100, containing 25 mg of carbidopa and 100 mg of levodopa.

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