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CombiPatch 0.05 mg estradiol/0.14 mg NETA per day (9 cm2) matrix transdermal system is used for continuous uninterrupted treatment applied twice weekly on the lower abdomen. A new system should be applied to the skin every 3 to 4 days (twice weekly) during a 28-day cycle. Nov 19, 2019 - CombiPatch® Dosing Regimens. There are two hormone therapy regimens that use CombiPatch: Continuous Combined regimen and Continuous Sequential Continuous combined regimen: 1 CombiPatch twice weekly for 28-day cycle; repeat. Continuous sequential regimen (use with 0.05mg/day estrogen patch): UseHow should I take CombiPatch? Put on a new combiPatch every 3 to 4 days, according to your doctor's instructions. it should be applied to clean, dry skin on the How to Apply the CombiPatch System. Tear open the pouch at the tear notch (do not use scissors). Remove the patch from the package and apply immediately. Holding the patch with the rigid protective liner facing you, remove half of the liner, which covers the sticky surface of the patch. CombiPatch® (estradiol/norethindrone acetate transdermal system) is an among different estrogen plus progestin combinations, doses, or routes of and INSTRUCTIONS FOR USE with patients for whom they prescribe CombiPatch. Apr 1, 2020 - The tables below summarize these results (intent-to-treat populations). Incidence of Endometrial Hyperplasia in a. Continuous Combined CombiPatch Regimen.