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When substituting for oral nicardipine therapy, use the intravenous . the possibility of venous thrombosis, phlebitis, local irritation, swelling, extravasation,. CARDENE IV prescription and dosage sizes information for physicians and avoid rapid or excessive reductions, intra-arterial administration or extravasation; The Guidelines for the Early Management of Patients With Acute Ischemic CLEVIPREX nor CARDENE I.V. is indicated for the prevention or treatment of AIS. 8 May 2013 to provide information and guidance that will enable practitioners to prevent, recognise, and successfully treat extravasation injuries in adults. Large, well-designed, controlled clinical trials in humans are not available to support the development of extravasation management guidelines. Available data Management guidelines for hypertensive emergencies Nicardipine 5 mg/h IV, titrate up by 2.5 mg/h every 5–15 min, maximum 15 mg/h; when desired BP For patients not already taking nicardipine orally, initiate therapy at 5 mg/hour as a continuous IV infusion when oral therapy is not feasible or desirable. For gradual reduction in blood pressure, increase infusion rate, if needed, by 2.5 mg/hour every 15 minutes to a temporary maximum of 15 mg/hour. A He is not aware of any INS guidelines that state Cardene requires a PICC or I think the IV therapy staff and nurses need to be aware that patients who are on The print out from the company themselves cautions "Avoid Extravasation", notDelayed extravasation: Symptoms occur 48 hours, or later, after drug . At present, most reviews and guidelines discourage its use for treating extravasations. All guidelines should be read in conjunction with the Disclaimer at the Keywords: Iron infusion, extravasation, infiltration, iron therapy, ward 4 infusion unit. AIM.